Virtual Insights into Pain: Agent-Based Modeling of Neural Activity in the Amygdala

Monday, April 8, 2024 - 11:00

427 Thackeray Hall

Speaker Information
Rachael Miller Neilan

Abstract or Additional Information

The central nucleus of the amygdala (CeA) is an area in the brain responsible for processing of pain information. I will discuss recent efforts to create a realistic and practical computational model of pain-related neural activity in the CeA. The model allows us to synthesize firing rate, connectivity, and location data from different wet-labs into a single framework to better understand how multiple neuron populations work together to modulate pain. I will demonstrate the model and showcase results highlighting the impact of spatial heterogeneity in model output. I will also highlight the ongoing contributions of undergraduate students to this research.